John Wildenthal
Program: Computational and Systems Biology
Current advisor: Jeffrey P. Henderson, MD, PhD
Undergraduate university: Ohio State University-Columbus
Research summary
I am in the lab of Dr. Jeffrey Henderson, studying surgical site infections. We are currently using metabolomic techniques to (1) look for early biomarkers of infection, before clinical symptoms are present (2) determine ways that bacteria interact with the host and each other during infections and co-infections using metabolites and their alterations.
Graduate publications
Heffernan JR, Wildenthal JA, Tran H, Katumba GL, McCoy WH, Henderson JP. 2024 Yersiniabactin is a quorum-sensing autoinducer and. mBio, 15(2)::e0027723.
Wildenthal JA, Schwartz DJ, Nolan NS, Zhao L, Robinson JI, Jones E, Jawa R, Henderson JP, Marks LR. 2023 Everything but the Kitchen Sink: An Analysis of Bacterial and Chemical Contaminants Found in Syringe Residue From People Who Inject Drugs. Open Forum Infect Dis, 11(1)::ofad628.
Zou Z, Potter RF, McCoy WH 4th, Wildenthal JA, Katumba GL, Mucha PJ, Dantas G, Henderson JP. 2023 E. coli catheter-associated urinary tract infections are associated with distinctive virulence and biofilm gene determinants. JCI Insight, 8(2):e161461.
Wildenthal JA, Atkinson A, Lewis S, Sayood S, Nolan NS, Cabrera NL, Marschall J, Durkin MJ, Marks LR. 2022 Outcomes of Partial Oral Antibiotic Treatment for Complicated S. aureus Bacteremia in People Who Inject Drugs. Clin Infect Dis, ciac714(epub ahead of print):.
Marks LR, Calix JJ, Wildenthal JA, Wallace MA, Sawhney SS, Ransom EM, Durkin MJ, Henderson JP, Burnham CD, Dantas G. 2021 Staphylococcus aureus injection drug use-associated bloodstream infections are propagated by community outbreaks of diverse lineages. Commun Med (Lond), 1():52.