Joseph Krambs

Program: Molecular Genetics and Genomics

Current advisor: Daniel C. Link, MD

Undergraduate university: Middle Tennessee State University

Research summary

Graduate publications
Yao JC, Oetjen KA, Wang T, Xu H, Abou-Ezzi G, Krambs JR, Uttarwar S, Duncavage EJ, Link DC. 2022 TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche. J Clin Invest, 132(11):e154092.

Li S, Yao JC, Oetjen KA, Krambs JR, Xia J, Zhang J, Schmidt AP, Helton NM, Fulton RS, Heath SE, Turnbull IR, Mbalaviele G, Ley TJ, Walter MJ, Link DC. 2022 IL-1b expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function. Blood, ():blood.2022016084.

Krambs JR, Monlish DA, Gao F, Schuettpelz LG, Link D. 2021 Microbiota Signals Suppress B Lymphopoiesis With Aging in Mice. Front Immunol, 12():767267.

Krambs JR, Abou Ezzi G, Yao JC, Link DC. 2020 Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions. PLoS ONE, 15(5)::e0233751.

Kapoor V, Collins A, Griffith K, Ghosh S, Wong N, Wang X, Challen GA, Krambs J, Link D, Hallahan DE, Thotala D. 2020 Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow. Oncotarget, 11(19):1681-90.

Abou-Ezzi G, Supakorndej T, Zhang J, Anthony B, Krambs J, Celik H, Karpova D, Craft CS, Link DC. 2019 TGF-β Signaling Plays an Essential Role in the Lineage Specification of Mesenchymal Stem/Progenitor Cells in Fetal Bone Marrow. Stem Cell Reports, 13(1):48-60.

Zhang J, Supakorndej T, Krambs JR, Rao M, Abou-Ezzi G, Ye RY, Li S, Trinkaus K, Link DC. 2019 Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. J Clin Invest, 129(7):2920-31.