Louise Medina Bengtsson
Program: Cancer Biology
Current advisor: Sheila A. Stewart, PhD
Undergraduate university: University of Notre Dame
Research summary
Previous work from our lab has shown that elimination of senescent cancer-associated fibroblasts (senCAFs) in a breast cancer mouse model significantly reduces metastatic burden in the lungs. Additionally, we found that senCAFs improve the migration efficiency of tumor organoids in vitro, and that these senCAFs are present in circulating tumor cell clusters in the blood of tumor-bearing mice. Given these data, I am currently studying how senCAFs promote breast cancer metastasis, focusing on collective migration.
Graduate publications