Madison Daminato
Program: Unspecified
Current advisor:
Undergraduate university: University of Michigan-Ann Arbor
Research summary
My research interests focus on biomimetic materials and tissue constructs to advance patient care. Particularly, they lie in microfabricated tissues and biomimetic constructs, exploring cell-matrix interactions and tissue regeneration. This knowledge aims to innovate biomedical interventions and tissue replacements.
By replicating complex functions of tissues and organs on a microscale, I will study cell-matrix interactions in a controlled environment. I aim to develop technology to investigate how different cell types respond to various biochemical and biomechanical factors, a knowledge I have started to develop through projects like microfluidic artificial lungs, which study the effects of channel height on thrombus formation and size, and an arterial tissue model that investigates the effects of cytokines and shear stress profiles on protease activity. This technology is also crucial for understanding the mechanisms responsible for tissue regeneration, potentially identifying targets for disease reversal. Additionally, I am eager to adapt biomaterials and tissue constructs for patient-specific applications using bioprinting or patient samples.
Graduate publications