Rachel Mintz

Program: Biomedical Engineering

Current advisor: Gwendalyn J Randolph, PhD

Undergraduate university: Columbia University

Research summary
Effective treatment strategies to halt ovarian cancer peritoneal metastases are still lacking, which is problematic as few ovarian cancer cases are diagnosed prior to this stage. I aim to understand how the omentum, the earliest site of peritoneal metastasis, supports ovarian tumor seeding and dissemination. Ultimately, the insight gained will allow us to uncover more specific therapeutic strategies to improve outcomes for ovarian cancer patients with peritoneal metastasis.

Graduate publications
Lam SF, Bishop KW, Mintz R, Fang L, Achilefu S. 2021 Calcium carbonate nanoparticles stimulate cancer cell reprogramming to suppress tumor growth and invasion in an organ-on-a-chip system. Sci Rep, 11(1):9246.

Fan J, Cheney PP, Bloch S, Xu B, Liang K, Odonkor CA, Edwards WB, Basak S, Mintz R, Biswas P, Achilefu S. 2021 Multifunctional Thio-Stabilized Gold Nanoparticles for Near-Infrared Fluorescence Detection and Imaging of Activated Caspase-3. , 17(8):1182-1193.


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